Study to explore diverse interactions of amino acids and vitamin molecule in aqueous environment

Abstract

ABSTRACTPhysico-chemical study of solute–solvent interactions in phenylalanine, histidine and aqueous solution of nicotinic acid (vitamin) has been investigated by thermophysical properties. The apparent molar volume (ϕ), viscosity B-coefficient and molal refraction (RM) of phenylalanine and histidine have been studied in 0.01, 0.03 and 0.05 mol dm−3 aqueous vitamin solutions at different temperatures. Using the density data, Masson equation has been employed to obtain the limiting apparent molar volumes (ϕ) and experimental slopes (), which deduced the solute–solvent and solute–solute interactions, respectively. Using the Jones–Dole equation, the viscosity data were examined to determine the viscosity A and B coefficient. The Lorentz–Lorenz equation has been employed to determine the molar refractions (RM). The overall results established the strong solute–solvent interactions between the studied amino acids and vitamin mixture in the ternary solutions. UV-visible absorption spectra of the ternary solutions also stand in support of the results obtained.