Abstract
Methods: Consecutive patients with untreated CHD were enrolled in this investigator driven cross-sectional study in two EU centers. All the standard clinical and virological characteristics were collected. HDV RNA was quantified by sensitive and specific assays (Robogene or a local validated in-house assay). Serum HBV RNA was quantified by an automated real-time PCR based investigational assay (cobas® 6800, Roche Diagnostics, Pleasanton, Ca, USA, LLOQ 10 cp/mL) while serum HBcrAg levels were measured using LUMIPULSE® G HBcrAg assay (Fujirebio Europe, LLOQ 3 log10 U/mL).
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