Abstract
Introduction : Intra ocular pressure is an essential entity in maintaining the structural and functional integrity of eye ball. It varies in regular cycle in the normal eye for 24hour. In the present study, the diurnal variation of Heart rate, intra ocular pressure, systolic, diastolic, pulse and mean arterial pressures from 6AM to 6PM with every 2 hour interval was investigated. Methodology: The present study included 100 normal male healthy subjects from the Gulbarga city, recruited after their informed and written consent. Intra ocular pressure, Heart rate, Blood pressure, Temperature, Urine output and respiratory rate per minute was investigated in all the subjects. Diurnal variation of Intra ocular pressure, Blood pressure, heart rate was measured at every 2hrs from 6AM to 6PM. Result: The diurnal variation of Intra Ocular Pressure was significantly high (p<0.05). The diurnal variation of Heart Rate and Blood Pressure showed variations from 6AM to 6PM within physiological limits. Discussion: The diurnal variation of Intra Ocular Pressure, Heart Rate and Blood Pressure in early morning and at evening might be due to the combined homeostatic mechanism of autonomic nervous system and glucocorticoid release. Conclusion: Hence intra ocular pressure fluctuation more than 30 mmHg during diurnal variation water has diagnostic value towards development of latent Glaucoma.
Highlights
Intra ocular pressure is an essential entity in maintaining the structural and functional integrity of eye ball
The persistent rise in intra ocular pressure of the eye more than 22 mm Hg is called ocular hypertension. Both hypo and hypertension have got adverse effect, like hypotension leads to retinal detachment and shrinkage of eye ball, while increased intra ocular pressure leads to a clinical disease complex known as Glaucoma[2], where there is insidious and progressive death of optic nerve resulting in permanent blindness of eye
The heart rate and systolic blood pressure, diastolic blood pressure, pulse pressure and mean arterial pressure were measured from 6.00 AM to 6.00 PM with an interval of every two hours. 2.1 Statistical analysis: The data collected was represented as Mean ± S.D. and was subjected to statistical analysis by one way ANOVA using SPSS Version- 12
Summary
Intra ocular pressure is an essential entity in maintaining the structural and functional integrity of eye ball It varies in regular cycle in the normal eye for 24hour. Diurnal variation of Intra ocular pressure, Blood pressure, heart rate was measured at every 2hrs from 6 AM to 6 PM. The intra ocular pressure is an essential entity in maintaining the structural and functional integrity of the eye ball. Disruption in any of these three levels can induce altered new level of intra ocular pressure These factors are re-established to normal when the rate of entry of aqueous humour again equals its elimination rate.
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