Abstract
Simple methods for the preparation of water soluble dithiocarbamates, several of which are newly synthesized, are presented along with some of their physical properties and a preliminary examination of their acute toxicity and their ability to offset acute mercuric chloride poisoning. Such compounds, although they do not possess great thermal stability, recommend themselves for wider application because of their ease of preparation and general effectiveness in binding those metal ions which form insoluble sulfides. Those compounds which possess an appreciable water solubility because of polar groups possess a rather slight degree of toxicity when administered intraperitoneally to mice. Some of these compounds are clearly effective as antidotes for acute mercury poisoning.
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