Abstract
Distribution patterns of drug resistance Mycobacterium tuberculosis among HIV negative and positive tuberculosis patients in Western Kenya
Highlights
Anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis
Our study showed that Mycobacterium tuberculosis drug resistance among HIV negative and positive cases in Western Kenya was prevalent in all the 10 counties surveyed
Drug resistant M. tuberculosis strains prevalence is still high among HIV negative and positive patients in Western Kenya with the most affected being HIV negative TB patients
Summary
Anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. This study aimed at determining Mycobacterium tuberculosis drug resistant strain distribution pattern in 10 counties of Western Kenya among HIV positive and negative patients. Infection is almost exclusively transmitted airborne when an individual inhales live bacteria released in aerosolized microdroplets/droplet bioaerosols that are generated when an individual with active and advanced symptomatic pulmonary TB disease laughs, sneezes, coughs or is talking. Such aerosols can remain airborne and infectious for several hours, be carried in the air and accumulate in poorly ventilated environments. Factors that increase risk of transmission include: the bacilli load/cfu in the airborne bioaerosols, the concentration and distribution of bioaerosols in the environment; and prolonged exposure to bacillaryladen aerosols [4]
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