Abstract
Xanthurenic acid 8-O-β- d-glucoside is a side metabolite of the tryptophan-xanthommatin pathway in Drosophila melanogaster, that is accumulated in some eye-color mutants. Since this compound had only been found in this species, we have analyzed 29 other Drosophila species for the occurrence of this compound using cellulose thin-layer chromatography. Xanthurenic acid glucoside was detected in 10 of them (8 of them belong to the Sophophora subgenus). In these species xanthurenic acid glucoside, as well as other metabolites of the final steps of the dihydroxanthommatin pathway (3-hydroxykynurenine, xanthurenic acid and dihydroxanthommatin) were quantitated in order to gain a better understanding of the relationships of the metabolites of this pathway.
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