Abstract
An automated screening method for the atypical cholinesterase gene (E1a) is described. By this method, 97 heterozygotes but no homozygotes for the atypical allele were found in a series of 3,143 Norwegian blood donors (gene frequency 0.0154). The method seems useful in the screening of large series of sera for the atypical enzyme also in samples stored frozen for many years.
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