Distribution and drug resistance of pathogenic bacteria from urinary tract infection

Abstract

Objective To investigate the distribution of pathogens and drug resistance in patients with urinary tract infection. It provides help and guidance to our hospital for clinical diagnosis and rational use of drugs. Methods Urinary urine samples of our outpatient and inpatient patients(January 2008-December 2009) with urinary tract infection were collected. Conventional method of cultivation,production by the German Siemens Walk Away40SI microbial susceptibility test system for identification and drug resistance of 295 strains of pathogens isolated from the strain identification. Results Two hundred and ninety-five strains of pathogens were isolated,Gram-negative bacteria 204(69.2%),Gram-positive bacteria 67(22.7%),24 strains of fungi(8.1%).The top five pathogens followed by Escherichia coli 150(50.8%), Enterococcus 30(10.2%),24 strains of coagulase-negative staphylococci(8.1%),Proteus 12(4.1%), Klebsiella pneumoniae 12(4.1%).Drug Resistance shows that:Enterobactreiaceae remains 100% sensitivity to Carbapenems,strong sensitivity toamikacin nitrofurantoin,high resistance to other antibiotics;resistant in gram-positive cocci situation is very serious. Conclusions The most important pathogen of urinary tract infection,Escherichia coli,is a serious pathogen resistance and multidrug resistance,clinicians should inspect actively and use antibiotics rationally according to the results of urine culture. Key words: Urinary tract infection; Pathogens; Drug resistance