Distinguishing Mass Loading Effect from Damping Loading Effect of Piezoelectric Immunosensor Using Energy Transfer Model

Yan Chen,Wen Cao,Feng Tan

doi:10.18494/sam.2019.2495

Abstract

Distinguishing Mass Loading Effect from Damping Loading Effect of Piezoelectric Immunosensor Using Energy Transfer Model

Highlights

In recent years, the attention of many researchers in the fields of medicine and electronic information has been concentrated on piezoelectric (PZ) immunosensors
2nfq2 μq ρq where Δm is the weight change on the surface quartz crystal, S is the area of the electrode surface, n is the overtone number, fq is the fundamental frequency of the quartz crystal, μq is the shear modulus of quartz, ρq is the density of quartz, and Δfm is the observed frequency shift caused by the mass loading effect
The change in frequency can be considered a consequence of the changed mass of the NuTu-19 cell immobilization; in other words, the damping loading effect of the NuTu-19 cell film can be ignored in gas phase measurements

Summary

Introduction

The attention of many researchers in the fields of medicine and electronic information has been concentrated on piezoelectric (PZ) immunosensors. Yang et al[1] and Chen et al[2] used PZ immunosensors to detect cervical and ovarian cancer in women; Montoya et al[3] used them to detect tuberculosis; Pirinçci et al[4] used them to detect ochratoxin A. Test results showed that in addition to some influencing factors, such as test temperature, humidity, and circuit jitter, there are still errors. These errors are sometimes large, and more severe cases can result in false positive rates. The reason for this is that the application is based only on the Sauerbrey theory.[5]

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Conclusion