Disseminated neonatal Trichosporon beigelii infection: Successful treatment with liposomal amphotericin B

Abstract

Trichosporon beigelii, normally a low grade pathogen, can cause disseminated infection in neonates with a high associated mortality. We report a case in a 25-week gestation, 950 g female infant who had evidence of disseminated infection yet survived after treatment with the Liposomal form of Amphotericin B without any evidence of drug-induced adverse effects. A review of previous reported cases shows this form of disseminated mycosis to be rare and almost always fatal.