Abstract
The resistance to disease caused by the Aeromonas sobria in three genotypes of tilapia, Nile tilapia ( Oreochromis niloticus), blue tilapia ( Oreochromis aureus) and their hybrid (female Nile tilapia×male blue tilapia) was studied . Based on comparison of median lethal dose (LD 50), functions of nonspecific immunity, including total amount of complements, bactericidal reaction by alternative pathway of complement (C 3 shunt), percentage of erythrocyte C 3b receptor aggregates, leukocyte phagocytic function, as well as erythrocyte active rosette of T lymphocyte, it is indicated that the hybrid has the highest resistance to the disease caused by A. sobria, while blue tilapia has the lowest resistance.
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