Abstract
The intestinal microecosystem plays an important role in the health and nutrition of host. According to the fourth, fifth and the sixth edition of the diagnosis and treatment scheme of Corona Virus Disease 2019 issued by National Health Commission of the PRC, the intestinal microecological regulator can be used in the critical illness to maintain the balance of intestinal microecology and prevent infection, however, the specific use information is lack. This article introduced the classification of intestinal microecological regulators and summaried the clinical use of intestinal microecological regulators in critically ill patients and those who have diarrhea , as well as the information about rational use of current clinical commonly used probiotics and pharmaceutical care of them, in order to provide reference for the clinicians about the rational use of probiotic in Corona Virus Disease 2019. Key words: Probiotics; Synbiotics; Lactobacillus; Saccharomyces; Coronavirus infections; Critical illness; Diarrhea
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