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https://doi.org/10.1016/j.bmcl.2015.01.024
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Cite Publication Date: Jan 22, 2015 | |
 Citations: 5 |
Affiliation: Arena Pharmaceuticals (United States)
The design and synthesis of two closely related series of prostacyclin receptor agonist compounds that showed excellent human IP receptor potency and efficacy is described. Compounds from this series showed in vivo activity after SC dosing in the monocrotaline model of PAH in rat.
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