Discordance in activated partial thromboplastin time and anti-factor Xa levels in COVID-19 patients on heparin therapy

Matthew Lawlor,Aakriti Gupta,Lauren S Ranard,Mahesh V Madhavan,Jianhua Li,Andrew Eisenberger,Sahil A Parikh,Sanjum S Sethi,Amirali Masoumi

doi:10.1016/j.thromres.2020.11.030

Discordance in activated partial thromboplastin time and anti-factor Xa levels in COVID-19 patients on heparin therapy

Matthew Lawlor, Aakriti Gupta + Show 7 more

Open Access

https://doi.org/10.1016/j.thromres.2020.11.030

Copy DOI

Journal: Thrombosis Research	Publication Date: Nov 28, 2020
Citations: 6	License type: NO-CC CODE

Affiliation: Columbia University Irving Medical Center

#aPTT In Patients #Abnormal Coagulation Parameters + Show 8 more

Abstract
Full-Text PDF
Similar Papers

Abstract

• aPTT correlates poorly with anti-Xa in COVID-19 patients receiving unfractionated heparin. • aPTT potentially underestimates heparin activity compared with anti-Xa in COVID-19 patients receiving unfractionated heparin. • Elevated fibrinogen levels did not correlate with refractory aPTT in COVID-19 patients.

Full Text