Dilated Cardiomyopathy in a Patient with Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome)

Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, is a rare pathology that belongs to a group of diseases characterized by necrotizing vasculitis of small and medium-sized systemic blood vessels. Symptomatic cardiovascular involvement occurs in 27%–47% of cases of EGPA and is one of the most severe manifestations. The diagnosis is usually confirmed by eosinophilic infiltration observed in tissue biopsy, but with the recent inclusion of cardiac magnetic resonance imaging (MRI), the former can be replaced. Early diagnosis is important because timely treatment is often associated with improvement.