Abstract
Leiomyoma is a benign neoplasm with smooth muscle differentiation. In the skin there are three well-characterized variants: (1) piloleiomyoma, which arises from arrector pili muscle; (2) angioleiomyoma, which arises from the smooth muscle of a vein; and (3) genital leiomyoma, which arises from the smooth muscle of the scrotum, vulva, or nipple.l-? Angioleiomyoma does not have a distinctive clinical appearance. Pain and tenderness are the only clinical characteristics that suggest the nature of the nodule, but not all angioleiomyomas are painful? Pain can be also a presenting symptom of other cutaneous neoplasms, such as glomus tumors, spiradenomas, angiolipomas, or neuromas. Therefore diagnosis of angioleiomyoma usually is established by histopathologic study of an otherwise nonspecific cutaneous nodule. Although examples of angioleiomyoma have been reported on the trunk and face and even in the oral cavity, 3. 4 the neoplasm most frequently appears on the extremities, especially the legs. To the best of our knowledge there are no reports of subungual angioleiomyoma, and only one example of this neoplasm, a slow-growing tumor of the fingertip, has been illustrated in an atlas of hand conditions. We report an example of subungual angioleiomyoma that was studied histopathologically and immunohistochemically.
Published Version
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