Diffusiophoresis of a Soft Particle as a Model for Biological Cells

Abstract

We derive the general expression for the diffusiophoretic mobility of a soft particle (i.e., polyelectrolyte-coated hard particle) in a concentration gradient of electrolytes for the case in which the particle’s core size is large enough compared with the Debye length. Therefore, the particle surface can be regarded as planar, and the electrolyte concentration gradient is parallel to the core surface. The obtained expression can be applied for arbitrary values of the fixed charge density of the polyelectrolyte layer and the surface charge density of the particle core. We derive approximate analytic mobility expressions for soft particles of three types, i.e., (i) weakly charged soft particles, (ii) soft particles with a thick polyelectrolyte layer, in which the equilibrium electric potential deep inside the polyelectrolyte layer is equal to the Donnan potential, and (iii) soft particles with an uncharged polymer layer of finite thickness.