Abstract
Gliotoxin was shown to exert a less inhibitory effect on standard virulent type 1 and 2 poliovirus strains than on attenuated homotypie strains. This did not apply to type 3 standard strains since the virulent Saukett virus proved to be inhibited to the same degree as the attenuated Leon 12a1b, WM III and USOL D bac strains. An increase in gliotoxin-resistance after several intra-human passages of different live polio vaccine strains occurred only in a vaccinee fed the type 1 LSc2ab strain.
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