Abstract

By techniques of brain stimulation, neural mechanisms initiating pseudopregnancy in rats were distinguished from other neural mechanisms controlling ovulation. Although ovulation can regularly be induced during late diestrus or proestrus by unilateral “electrochemical” stimulation of the medial preoptic area under pentobarbital, pseudopregnancy proved to be an infrequent sequel when such animals were observed for appropriate lengths of time. On the other hand, pseudopregnancy was regularly evoked by unilateral “electrical” stimulation of the tuberal region at sites and with electrical parameters not commonly yielding ovulation. “Electrochemical” stimulation in the present experiments was produced by a small direct current passed briefly through a stainless steel electrode. “Electrical” stimulation through either stainless steel or platinum electrodes was accomplished with trains of biphasic matched pairs of rectangular pulses. All electrodes were concentric bipolar units of 0.4 mm tubing with 0.13 mm core...

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