Different contrastinjection protocols for 64-slice spiral CT coronary angiography

Abstract

：0bjective To determinethe optimal contrast protocols for 64.slice spiral CT coronary angiography in order toreduce the volume of contrast injection.Methods One hundred fifty pailents scheduled toundergo 64-slice spiral CT coronary angiography were prospectively randomized into thefollowing five groups with different injection protocols:group l:uniphasic injectionwithout a flush;group 2:biphasic injection with a flush;group 3,group 4 and group5:triphasic injection with a diluted contrast material with 3:7.5:5.7:3 contrast/salineratio respectively.Attenuation was measured in the right atrium,right ventricle,leftatrium,left ventricle,ascending aorta,fight coronary artery and left coronary artery andanalyzed with single factor variance test(ANOVA).The quality the coronary artery imageswas evaluated and compared using person Chi-Square.Results The total contrast materialvohme were (67.0±5.3)ml,(59.9±4.9)ml,(62.9±3.2)ml,(69.2 4±5.7)ml and(70.9 4-4.6)ml infive groups respectively(F=27.43,P<0.01).Image quali～scores of coronary arteries were significant differentamong five groups(X2=18.81,P<0.05).There were signiflcandy differences in artifacts ofthe superior vena cava among five groups(X2=31.44,P<0.01).The artifacts in the superiorvena cava in group 1 was the most,and in group 2 was the least.The mean enhancement valuesof right and left coronary arteries in group 2 were significantly greater than those inother groups(F=2.47 and 4.10,P<0.05).The visualization of both left ventricle and rightventricle cavities W88 the best in group 3.Conclusion Biphasic injection and triphasicinjection are better than uniphasic injection for 64-slice spiral CT coronary angiographyand triphasic injecfion is better than biphasic injection for the visualization of bothleft ventricle and right ventricle cavities. Key words: Coronary vesseh; Tomography,X-ray computed; Contrast media