Abstract
Objective To explore the effects of nasal continuous positive airway pressure (NCPAP) versus nasal double level positive pressure ventilation (nBiPAP) in the prevention of extubation failure in premature infants with ultra low birth weight. Methods Eighty preterm infants weighing less than 1 000 g and admitted into the NICU of our hospital were selected as study objects. All the objects took non-invasive breathing. The objects were divided into an NCPAP group and an nBiPAP group according to the different ventilations. The first extubation failure rate, the blood gas indicators before and after the extubation, and the incidence of comlications were compared between these two groups. Results The first extubation failure rate was 7.5% in the nBiPAP group and 35.0% in the NCPAP group (P 0.05). Conclusion nBiPAP in the prevention of extubation failure in ultra-low birth weight premature children is better than NCPAP, but the safety aspect needs a large-scale long-term study. Key words: Nasal continuous positive airway pressure; Nasal double level positive pressure ventilation; Ultra low birth weight premature children; Extubation failure
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