Abstract
The aim of the study was to investigate the relationship between slow and forced vital capacity (SVC-FVC) difference with dynamic lung hyperinflation (DH) during the 6-min walking test (6MWT) in subjects with chronic obstructive pulmonary disease (COPD). Twenty-four subjects with COPD (12 males; 67 ± 6years; forced expiratory volume in first second [FEV1] 56 ± 18% predicted) performed lung function tests by spirometry and plethysmography. DH was assessed by serial measurements of inspiratory capacity (IC) performed during the 6MWT and defined as ∆IC ≥ 150mL or 10%. IC decrease significantly during the 6MWT (ΔCI: - 0.48±- 0.40L; P < 0.0001), and 18 individuals (75%) presented DH. There was significant difference when comparing IC measured at rest with the other serial IC measurements (P < 0.0001). Correlation between the SVC-FVC difference and DH during the 6MWT was r=- 0.38; P = 0.06. The SVC-FVC difference presented only weak correlation with the development of DH during the 6MWT in patients with COPD.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call