Abstract
Renin-angiotensin-aldosterone system blockade is one of the key therapeutic targets in the hypertensive patient because its overactivation is directly associated with a sustained elevation in systemic blood pressure and deterioration of the vascular system. The two main pharmacological groups, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, inhibit different levels of the system and share a large number of similarities and some differences in their clinical efficacy. Both groups share a substantial number of indications among hypertensive patients. However, some evidence hasangiohighlighted an individual effect of certain molecules, which should be considered to optimize antihypertensive therapy according to the latest guidelines. Recent evidence on antihypertensive treatment in diabetic patients with dual renin-angiotensin-aldosterone system blockade (KDIGO guidelines) does not support its generalized use due to the increased risk of cardiovascular events.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
