Dietary supplementation of red-osier dogwood polyphenol extract changes the ileal microbiota structure and increases Lactobacillus in a pig model

Shugui Zheng,Jichen Song,Xia Qin,Mei Liu,Kai Yang,Chengbo Yang,Charles M Nyachoti

doi:10.1186/s13568-021-01303-8

Shugui Zheng, Jichen Song + Show 5 more

Open Access

https://doi.org/10.1186/s13568-021-01303-8

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Abstract

Red-osier dogwood (ROD) extract contains a lot of polyphenols that have the potential for modulation of gut microbiota. However, little information is available about its prebiotic properties. This study investigated the impact of ROD polyphenol extract on the ileal microbiota with dietary supplementation of ROD polyphenol extract in a pig model. The data indicated that supplementation of ROD polyphenol extract significantly increased class Bacilli, order Lactobacillales and family lactobacillaceae. Within family lactobacillaceae, Lactobacillus was the main responder by increasing from 5.92% to 35.09%. Further analysis showed that ROD polyphenol extract improved two species Lactobacillus delbrueckii and Lactobacillus mucus. The results of this study suggested that ROD polyphenol extract has the potential to play prebiotic role and confer health benefit through modifying gut microbiota.

Highlights

Gut health is essential for overall physical health of humans and animals
Dietary Red-osier dogwood (ROD) polyphenol extract had no significant effect on performances in finishing pigs There was no significant effect on the average daily gain (ADG), average daily feed intake (ADFI) and F/G due to supplementation of ROD polyphenol extract (Table 2)
The effect of dietary supplementation of ROD polyphenol extract on volatile fatty acid production and pH To determine the effect of ROD polyphenol extract on the ileal fermentation parameters, the concentrations of acetate, propionate, butyrate, valerate, isovalerate, total volatile fatty acids (VFA) and ileal pH were determined

Summary

Introduction

Gut health is essential for overall physical health of humans and animals. There are an enormous number of microbes, most mainly bacteria, in human and animal intestines. Many of these bacteria, which are called commensal bacteria, are highly beneficial. Commensal bacteria play a crucial role in fermenting food, modulating the host immune response, protecting against infections, and regulation of host metabolism, etc. It is the balance between beneficial and harmful bacteria that determine the function of gut microbiota and health in general (Kevin et al 2005)

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