Abstract
BackgroundAlthough some studies have shown the associations between dietary patterns and the risk T2DM in a general population, the associations in middle-aged Chinese have been rarely studied to date. In this study, we aimed to characterize dietary patterns in Chinese adults aged 45-59y (n = 1918) and to evaluate the relationship between dietary patterns and the risk of T2DM.MethodsThe study population was a part of the population-based the Nutrition and Health Study conducted in the city of Hangzhou, Zhejiang Province, China. Dietary intake was assessed by using a validated food frequency questionnaire (FFQ). Multivariate logistic regression analyses were used to estimate the associations between dietary patterns and the risk of T2DM, adjusting for potential confounders.ResultsThree major dietary patterns were identified using factor analysis, including the traditional southern Chinese, the Western, and the grains-vegetables patterns. After adjusting for the potential confounders, subjects in the highest quartile of the Western dietary pattern scores had greater odds ratio(OR) for T2DM(OR = 1.28; 95% confidence interval (CI): 1.103–1.697; P = 0.02) than did those in the lowest quartile. Compared with those in the lowest quartile, subjects in the highest quartile of the grains-vegetables dietary pattern scores had a lower OR for T2DM (OR = 0.72; 95% CI:0.596–0.952; P = 0.04). Moreover, no significant association was found between the traditional southern Chinese dietary pattern and risk of developing T2DM.ConclusionsOur findings indicated that the Western dietary pattern was associated with an elevated risk, whereas the grains-vegetables dietary pattern was associated with a reduced risk of T2DM. Further researches are needed to confirm these findings.
Highlights
Some studies have shown the associations between dietary patterns and the risk Type 2 diabetes mellitus (T2DM) in a general population, the associations in middle-aged Chinese have been rarely studied to date
Limited attention has been given to the role of dietary patterns in the development of T2DM in a Chinese population.To the best of our knowledge, this study is the first to clarify the associations between major dietary patterns and the risk of T2DM in a middle-aged Chinese population
Our results indicated that the grains-vegetables dietary pattern was associated with a significantly decreased risk, while the Western dietary pattern was associated with increased risk for T2DM
Summary
Some studies have shown the associations between dietary patterns and the risk T2DM in a general population, the associations in middle-aged Chinese have been rarely studied to date. We aimed to characterize dietary patterns in Chinese adults aged 45-59y (n = 1918) and to evaluate the relationship between dietary patterns and the risk of T2DM. To date, data on the associations between dietary patterns and T2DM in the Chinese population are limited [13, 14], in a middle-aged population. To the authors’ knowledge, no previous epidemiological studies have reported the associations between dietary patterns and risk of T2DM in a middle-aged population in China. In the present study, we aimed to characterize dietary patterns in Chinese adults aged 45-59y and to evaluate the associations between dietary patterns and the risk of T2DM
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