Diastolic function of left ventricle and importance of tissue doppler echocardiography in patients with coronary artery disease and type 2 diabetes mellitus after coronary artery bypass grafting

Abstract

Objective. To analyze the influence of coronary artery bypass grafting CABG) on the diastolic function DF) in patients with coronary artery disease and type 2 diabetes mellitus with the preserved systolic function of the left ventricle LV) using tissue myocardial Doppler echocardiography TMD). The increase in the number of patients with type 2 diabetes mellitus type 2 DM) is one of the causes of a constant growth of the quantity of patients with coronary artery disease CAD). Taking into account the character of vascular bed lesion in patients with type 2 DM, revascularization of myocardium is significant for CAD treatment in this group of patients.
 Materials and methods. The study included 122 patients diagnosed coronary artery disease mean age 58.8 0.7 years, men 81.1 %), who underwent coronary artery bypass grafting. The patients were divided into two groups: group 152 patients with CAD without type 2 DM; group 270 patients with CAD and type 2 DM. To assesss the diastolic function using pulse-wave Dollper PWD), there were estimated the velocity and time characteristics of the transmitral blood flow by means of TMD myocardium movement velocity at the level of the mitral valve fibrous ring.
 Results. The quantity of the detected patients with diastolic dysfunction DD) when using both PWD and TMD with type 2 DM 85.7 %, without type 2 DM 65.3 %) in both groups was higher compared with PWD applied alone with type 2 DM 77.3 %, without type 2 DM 59.6 %) p 0.001).
 Conclusions. Among CAD patients with preserved systolic function of the left ventricle, who underwent CABG and have type 2 DM, the use of both PWD and TMD is more preferable for revealing DD and dynamic postoperative observation.