Abstract
Novel chiral glycinate derivatives (S)-6 and (S)-7 contain- ing the a-phenylethyl group, were prepared and studied as potential precursors of enantiopure a-substituted-a-amino acids. In particu- lar, the alkylation of enolate (S)-7-Li showed substantial (78:22 dr) stereoinduction by the N-(1-phenylethyl)benzamide chiral auxiliary. Addition of DMPU showed no appreciable effect upon the diastere- oselectivity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
