Diagnostic value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in brucellosis

Abstract

Objective To investigate diagnostic value of mean platelet volume(MPV), neutrophil to lymphocyte ratio(NLR) and platelet to lymphocyte ratio(PLR) in brucellosis disease. Methods In this retrospective study, we reviewed 200 cases of patientswith confirmed brucellosis in the General Hospital of Heilongjiang Province Land Reclamation Bureau during June 2016 to June 2017, 200 healthy people with matchedage and sex were recruited as control group.White blood cell (WBC) count, neutrophil count, lymphocyte count, platelet count, hemoglobin (Hb), MPV, NLR and PLR were determined.In addition, inflammatory markers such as erytrocyte sedimentation rate(ESR) and hypersensitive C-reactive protein (hs-CRP) were also analyzed. Results WBC count, neutrophil count, Hb and NLR were significantly different between the patient group and the control group(P 0.05). NLR was more significantly different between patients with arthritis and that without arthritis(P=0.009). The difference of Hb was also significant between patients with arthritis and without arthritis(P<0.05). ESR and (hs-CRP) were also different between patients and controls (P<0.05). Conclusion NLR can be used as an inflammatory marker for Brucellosis.In addition, NLR is more valuable for the diagnosis of patients with brucella arthritis. Key words: Brucellosis; Neutrophil to lymphocyte ratio; Platelet to lymphocyte ratio