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Abstract
The study was designed to elucidate the informative value of chronaximetry for the quantitative assessment of denervation-induced defects of m. soleus in patients with diabetic neuropathy. Conditions are clarified under which chronaximetric measurements disagree with the position of the IT hyperbola; this discrepancy lowers substantially the informative value of these characteristics as a measure of the degree of manifestation of diabetic neuropathy. The value of chronaximetry for this purpose is markedly surpassed by that of the position of the vertex of IT hyperbola. Two approaches are proposed to the simplified and exact calculation of the position of the vertex of IT hyperbola. The length of the excitation pulse obtained by these methods (CRP6 and TGT parameters) may be used, similar to chronaximetric measurements, both for the evaluation of neuropathic changes and for the choice of optimal electrostimulation technique.
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