Abstract

05Sep 2019 DIAGNOSTIC IMPORTANCE OF MATRIX METALLOPROTEINASE 2 AND 9 AS ADDITIONAL BIOMARKERS IN THE SERA OF BREAST CANCER PATIENTS. Solanki Sulabhsinh and Shah Menka. Department of Microbiology, Shree M. & N. Virani Science College, YogidhamGurukul, Kalawad Road, Rajkot-360005, Gujarat, India. Department of Pathology, Pramukh Swami Medical College, Karamsad-388325, Gujarat, India.

Highlights

  • Tumor invasion and metastasis are the critical steps in breast cancer, leading to detrimental conditions

  • Materials & Methods: Sera was collected from 70 breast cancer patients before surgery or who underwent surgery and 50 healthy controls and the activity levels of Matrix metalloproteinase (MMP)-2 and MMP-9 were quantified by performing gelatin zymography

  • The results show that average levels of both MMP-2 and MMP-9 were significantly higher in sera of breast tumor patients as compared to sera of benign breast disease and control group (p

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Summary

RESEARCH ARTICLE

DIAGNOSTIC IMPORTANCE OF MATRIX METALLOPROTEINASE 2 AND 9 AS ADDITIONAL BIOMARKERS IN THE SERA OF BREAST CANCER PATIENTS. Solanki Sulabhsinh[1] and Shah Menka[2]. Virani Science College, YogidhamGurukul, Kalawad Road, Rajkot-360005, Gujarat, India. 2. Department of Pathology, Pramukh Swami Medical College, Karamsad-388325, Gujarat, India

Introduction
Results
Conclusion
Stage IV

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