Abstract
Abnormal spontaneous eye movements, including nystagmus and saccadic intrusions, are often encountered in neurologic practice and can cause disabling visual symptoms, such as oscillopsia and blurred vision. This article reviews the spectrum of abnormal spontaneous eye movements and describes their characteristics, etiology, and management. The number of prospective, controlled, and masked clinical trials evaluating candidate treatments for abnormal spontaneous eye movements has increased significantly over the past decade. The findings of recent clinical trials are highlighted, and the dosing and potential side effects of proposed medical treatments are summarized. Abnormal spontaneous eye movements are often encountered in neurologic practice. Recent clinical trials provide an evidence base to guide treatment decisions for these disorders.
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