Abstract
Sera from 25 healthy subjects, 10 patients with benign neoplastic lesions and 30 patients having malignant lesions of Head and Neck region, were analysed for protein bound fucose levels. The levels were significantly elevated in the malignant group, as compared to other two groups. In 10 cases of the malignancy, the fucose levels were repeated after one week of complete removal of the growth, whence the values were found to be lowered to normal range in 7 patients. Thus serum protein bound fucose estimation is a useful adjunct to clinical examination in the diagnosis and prognosis of Head and Neck malignancies.
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