Diagnosis value of abnormal distribution of electrophysiological parameters in Guillaln-Barre syndrome

Abstract

Objective To investigate diagnosis value of abnormal distribution of electrophysiological parameters in Guillain-Barre syndrome. Methods 40 cases of Guillain-Barre syndrome were chosen as an object of study, all patients electrophysiological examination. Record limbs on both sides, upper and lower extremities and proximal and distal motor nerve distal latency （ DML）, motor conduction velocity （ MCV ）, compound muscle action potential （CMAP） and sensory conduction velocity（SCV） were recorded. Results F wave latency mildly abnormal, moderately abnormal and severe abnormalities were 18.3 % ,6.2 % and 5.3 %, totaling 29.8 %, F-wave occurrence rate mildly abnormal,moderately abnormal and severe abnormalities were 9.3 % 9.8% and 15.6% ,totaling 66.9%. Abnormal sensory conduction velocity was 57.5% ,motor conduction velocity anomaly was 75.7%, there was a statistically significant difference between the two groups （x^2 = 5.34, P 〈 0. 05 ）. bilateral tibial nerve tests showed mild, moderate and severe in patients with H-reflex abnormality rates were 78.0% ,80.9% and 100.0% ,among the three comparison （ Uc = 1.47 ,P 〉 0.05 ）. 3 proximal and distal motor nerve severe damage rates were 48.3 percent and 74.5 percent, the difference was statistically Significant （ x^2= 9.86, P 〈 0. 05 ）. Severe upper limb proximal nerve damage was 51.4%, significantly lower than 71.6% of the distal upper extremity, lower extremity proximal nerve severe damage to 44.2 % , significantly lower than the 81.6% of distal lower extremity between them were statistical difference （x^2 = 8.86,12.43, all P 〈 0.05 ）. Conclusion Electrophysiological parameters detection Guillain-Barre syndrome has a high value, which can be accurate response in patients with neurological damage. Key words: Guillain-Barre syndrome ; Nerve conduction; Physiology; Nerve