Diagnosis and treatment of sepsis associated encephalopathy

Abstract

Sepsis-associated encephalopathy(SAE), as a relatively common complication of sepsis, is associated with mortality and poor prognosis.Its main symptoms are disturbed cognitive functions and consciousness, including decreased attention, delirium, lethargy, coma, mood changes.At present, the pathogenesis of SAE has not been clearly explained, and the diagnosis and treatment are still controversial.Many of the survivors suffer from long-term cognitive impairment, which imposes heavy burdens on patients, families and society.Therefore, SAE needs to attract the attention of clinicians. Key words: Sepsis; Sepsis associated encephalopathy; Sepsis-associated delirium