Abstract
Sepsis associated encephalopathy(SAE)is the most common form of encephalopathy in the pediatric intensive care units and might appear before other systemic features of sepsis.The pathogenesis of SAE is complex and not clear.SAE causes increased morbidity and mortality but has limited therapeutic options.SAE has become a hot issue in critical care medicine. Key words: Sepsis; Sepsis associated encephalopathy; Inflammation
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