Abstract
The prostate of mammals in general is a purely sexual gland, often separated by a considerable space from the bladder, and entirely independent of this organ; in some animals (e.g., the ram) the prostate is lacking; in others (the squirrel) it is entirely suburethral. In some mammals, notably man, the prostate presents an intimate anatomic relation with the bladder; its muscular fibers completely encircle the urethro-vesical orifice, and perform the function of a vesical sphincter. The human prostate lies at the junction of the genital and urinary channels, and it is intimately associated in function with both; it, moreover, almost includes that vestige of the Mullerian duct, the prostatic utricle; through it and around it courses the blood to and from the bladder. While the etiology of prostatic enlargement still remains a matter of speculation, it is certain that the earliest clinical symptoms are due to vascular engorgement of the
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