Abstract
Diabetic neuropathy(DN) is a common troublesome ramification of diabetes mellitus impacting at least 50-60% patients of diabetes with multiple complication result in nerve damage, tingling, muscle wastage, sharp pains, burning and numbness in peripheral extremities more often experience pain in legs and feet. Hyperglycemia presents a central role in progression of DN that causes variations in the blood vessels providing blood to the peripheral nerves; metabolic diseases such as initiation of the polyol pathway, myo-inositol depletion, genetic deviations and elevated non-enzymatic glycation which causes the generation of free radicals or oxidative stress. Intense Glycemic control is vitalto the ultimate prevention of DN. Apart from allopathic treatments, there are various alternative treatments like herbal based therapies, acupuncture therapies and physiotherapies are used to improve pain and other symptoms of DN and its related complications. This review provides a summary of various therapies of DN for treatment and its management.
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