Abstract
Dexmedetomidine is a sedating α-2 agonist that doesn't impair respiratory drive. In this multicenter study, investigators randomized 74 intensive care unit (ICU) patients with agitated delirium to receive either dexmedetomidine or placebo for ≤7 days. All patients were receiving mechanical ventilation and remained intubated only because lowering sedation levels to allow extubation would …
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