Abstract
Background and Objectives: We evaluated the effect of adding dexmedetomidine to ropivacaine for axillary brachial plexus blockade. The primary endpoints were the onset and duration of sensory and motor block and duration of analgesia. Methods: Eighty patients scheduled for elective forearm and hand surgery were divided into 2 equal groups in a randomized, double-blind fashion. The 4 main nerves in the axilla (musculocutaneus, radial, median, ulnar) were identified using neural stimulation. Patients were assigned randomly into 2 groups. In group R (n=40), 40ml (200 mg) of 0.5% ropivacaine +1ml saline and in group RD (n=40), 40ml (200 mg) of 0.5% ropivacaine +1ml dexmedetomidine (50
Highlights
Ropivacaine is a local anesthetic with long duration of action, having similar pharmacology to bupivacaine; it has a wider safety margin and was shown to possess less cardiotoxicity in comparison with bupivacaine
We investigated the effect of adding dexemedetomidine to ropivacaine for axillary brachial plexus blocks
In group RD, bradycardia was observed in 7 patients, and all of these patients were treated with atropine
Summary
Ropivacaine is a local anesthetic with long duration of action, having similar pharmacology to bupivacaine; it has a wider safety margin and was shown to possess less cardiotoxicity in comparison with bupivacaine. We investigated the effect of adding dexemedetomidine to ropivacaine for axillary brachial plexus blocks. Our primary endpoints were the onset time and duration of motor and www.ssjournals.com sensory blocks. We evaluated the effect of adding dexmedetomidine to ropivacaine for axillary brachial plexus blockade. The primary endpoints were the onset and duration of sensory and motor block and duration of analgesia. Motor and sensory block onset times, block durations, and duration of analgesia were recorded. Sensory and motor block onset times were shorter in group RD than in group R (P
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