Abstract
Resting membrane potentials of zona fasciculata-reticularis cells of the rat adrenal gland varied with age. The mean membrane potentials of newborn rat adrenal cells was −56.4 ± 0.7 mV in the first week of life. The mean potential increased slightly to −61.9 ± 0.8 mV in the second week and then decreased with age to a mean of −38.5 ± 0.8 mV in 25–50 week old rats and of −25.9 ± 1.9 mV in 100 week old rats. The changes in membrane potential may correlate with the indices of adrenocortical growth and activity.
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