Abstract

We describe the development, construction and preliminary results obtained with medium-size Multi-Gap Resistive Plate Chambers prototypes designed to detect and localize 511keV photons for Positron Emission Tomography imaging applications. The devices are intended for in-beam monitoring of the treatment plans throughout deep tumor therapy with hadron beams; emphasis is put on achieving coincidence time resolutions of few hundred ps, in order to exploit optimized reconstruction algorithm and reduce the heavy non-correlated background contributions distinctive of this operation. Using technologies developed for high energy physics experiments, the detectors can be built for covering large areas, thus leading the way to the conception of full-body PET systems at low cost.

Highlights

  • Positron Emission Tomography (PET) performed with the injection of site-specific positron-emitter tracers in the patient is one of the most powerful diagnostic techniques employed to localize invasive neoplasms

  • With the on-going commissioning of dedicated tumor treatment centers exploiting ion beams for patient irradiation, a need has aroused to develop in-beam imaging and diagnostic techniques which, adding to conventional X-ray radiography, Positron Emission Tomography and Computer Assisted Tomography, aim at improving the patient quality assurance during or shortly after the treatments

  • In the framework of the European FP7 Collaborative Project ENVISION (European NoVel Imaging Systems for ION therapy), several TOF-PET approaches have been studied, based on the use of scintillators with very fast readout, or on the use of Multi-Gap Resistive Chamber detectors; the latter development is described in this note

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Summary

Introduction

Positron Emission Tomography (PET) performed with the injection of site-specific positron-emitter tracers in the patient is one of the most powerful diagnostic techniques employed to localize invasive neoplasms. With the on-going commissioning of dedicated tumor treatment centers exploiting ion beams for patient irradiation (hadrotherapy), a need has aroused to develop in-beam imaging and diagnostic techniques which, adding to conventional X-ray radiography, Positron Emission Tomography and Computer Assisted Tomography, aim at improving the patient quality assurance during or shortly after the treatments. In the framework of the European FP7 Collaborative Project ENVISION (European NoVel Imaging Systems for ION therapy), several TOF-PET approaches have been studied, based on the use of scintillators with very fast readout, or on the use of Multi-Gap Resistive Chamber detectors; the latter development is described in this note. A comparative study of the two approaches can be found in Ref. [1]

Multi-Gap Resistive Plate Chambers
Detection of 511 keV photons
Choice of materials and geometry
MRPC design for PET
Front-end electronics
Detection efficiency for 511 keV photons
Timing calibrations and determination of the longitudinal coordinate
Coincidence Time Resolution
10. Conclusions and summary
Methods
Instruments and Methods

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