Abstract
This chapter discusses the aspects of the development of the hippocampus and the fascia dentata in the rat. The emphasis is placed on the developmental changes that take place during the first postnatal month. To illustrate the different developmental stages, including the laminar differentiation of the afferent fiber systems, results obtained with the Timm sulfide silver method are used. This histochemical method provides an excellent means for monitoring and screening en bloc the development of the afferent systems to the hippocampal region. The chapter presents examples of the experimental approaches, which involve the hippocampus and the fascia dentata and help clarify which factors are important for the formation and laminar segregation of nervous connections. The chapter also presents the preliminary results obtained by transplantation of hippocampal and dentate tissue from neonatal rats into the central nervous system (CNS) of littermates and adult rats.
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