Abstract
BackgroundAnopheles sinensis is a major vector of malaria and among the dominant species in Shandong province of China. Insecticide resistance is an important threat to vector-borne disease control. However, there are only few reports about insecticide resistance of An. sinensis populations from Shandong province.MethodsFrom 2003 to 2012, six districts in Shandong province were selected as the study areas. Insecticide susceptibility bioassay were tested on F1 progeny of An. sinensis to 4% DDT, 0.05% deltamethrin, 0.15% cyfluthrin, and 5% malathion, using the standard WHO resistance tube assay.ResultsThe resistance status of An. sinensis showed a significant decrease in the mortality rates in DDT, deltamethrin and cyfluthrin during the past ten years. Whereas obvious increase of mortality to malathion was observed throughout the assay, ranging from 47.37% to 86.62%.
Highlights
Anopheles sinensis is a major vector of malaria and among the dominant species in Shandong province of China
The bioassay results were summarized in three resistance classes as defined by WHO, susceptible if mortality was 98% or higher, possible resistant if mortality was 80–97%, and resistant if the mortality was less than 80% [20]. This is the first investigation of malaria vectors susceptibility to insecticides in Shandong province recently
The study demonstrated that field populations of An. sinensis from Shandong province developed high resistance to three insecticides tested, including DDT, deltamethrin and cyfluthrin
Summary
Anopheles sinensis is a major vector of malaria and among the dominant species in Shandong province of China. Insecticide resistance is an important threat to vector-borne disease control. There are only few reports about insecticide resistance of An. sinensis populations from Shandong province. The mosquito Anopheles sinensis is a major vector of human malaria in southeast Asia [1,2,3], and among the dominant species in Shandong province of China [4,5]. In the early 1960s and 1970s, Shandong province used to be an endemic region of malaria, where two largescale outbreaks had occurred with an annual infection of six million and four million, respectively. In order to combat malaria, vector control is still indispensable in endemic foci [6].
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