Development of industrial technology of plant substance of cultivated parsnip herb thick extract

Abstract

The aim of the work is to develop the industrial technology of domestic phyto-substance of cultivated parsnip herb thick extract (CPHTE) with the aim of its further introduction into a tablet dosage form of cardioprotective action. Materials and methods. As an object of research, the experimental samples of parsnip herb (Pastinacae sativae herba) of the domestic selection of the Petryk variety, harvested on the experimental fields of the Institute of Vegetable and Melon Growing of the National Academy of Agrarian Sciences of Ukraine (Kharkiv region) were used to obtain the plant substance CPHTE (Pastinacae sativae herbae extractispissi). Results. The results of experimental research were used while development of a block scheme of the production technological process of plant substance CPHTE and an apparatus scheme tested in industrial conditions of LLC Pharmaceutical Company “Zdorovye” (Kharkiv, Ukraine) and control technological parameters for each stage of the technological process for manufacturing the developed thick extract have been established. Conclusions. The technology of the domestic plant substance CPHTE production, as well as the blocking scheme of the technological process, and the apparatus scheme tested in industrial conditions of LLC Pharmaceutical Company “Zdorovye” (Kharkiv) had been theoretically substantiated and experimentally developed. The results of the experiment were used in the development of methods for quality control projects and technological regulations for the developed plant substance.