Abstract
The acute effects of medial (VMH) and lateral (LH) hypothalamic lesions on stomach morphology, motor activity, and feeding behavior were compared in two experiments. Rats received VMH or LH lesions and were sacrificed 4, 8, or 24 h later. Both lesions produced high activity counts at 4 h and a comparable number of ulcers, starting at the earliest interval tested. Neither VMH nor LH lesions produced acute changes in other organs, such as the adrenals, thymus, or spleen. In a second experiment, quantitative measures of stomach pathology did not indicate significant differences between ulceration produced by VMH and LH lesions in 24 h. A separate group receiving VMH lesions showed pronounced hyperphagia and hyperdipsia immediately after the lesion, while LH rats were aphagic and adipsic. Motor activity levels after the lesions correlated positively with ulcer incidence and severity. Possible relations between these acute behavioral and visceral effects of hypothalamic lesions are discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
