Abstract
To reduce the circulation path of the output current of traditional electroacupuncture (TEA) process in the body, a simple single-acupoint electroacupuncture (SEA) frame was designed and the acupuncture effect of SEA was evaluated through Hou-san-li (ST-36) and Qian-san-li (LI-10) acupoints. Forty-two healthy New Zealand rabbits were randomly divided into seven groups and underwent acupuncture for 20 min in an awake state. Blood samples aseptically collected from the ear vein 3 h before acupuncture and 0, 3, 6, 9, 12 and 24 h after acupuncture were used for the detection of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase MB (CK-MB) and motilin (MTL) in serum. The simple SEA frame was developed successfully, and the acupuncture results showed that the serum AST and ALT levels were significantly higher at 3 h after TEA with high frequency (p < 0.01) compared with the control group. Regarding serum CK-MB levels, no significant differences were found after SEA or TEA stimulation (p > 0.05). Serum MTL levels were significantly increased at 0 h after SEA and TEA (p < 0.05), but there were no significant differences at other time points after SEA and TEA treatment (p > 0.05). SEA not only maintains the effect of TEA but also shortens the circulation loop of the electroacupuncture (EA) current in the body, which effectively avoids body injury.
Highlights
Acupuncture is a traditional therapy with a history of more than 3000 years and has been accepted worldwide as a complementary and alternative medicine
In experimental research or clinical treatments, two or more different acupoints of the body should be connected, so that the electric current forms a circuit in the body to achieve the purpose of treatments
There is great potential for electric currents to damage the body during electroacupuncture therapy in these animals [7]
Summary
Acupuncture is a traditional therapy with a history of more than 3000 years and has been accepted worldwide as a complementary and alternative medicine. In 1810, the French physician Louis Berlioz first proposed the idea of treating diseases with currents during acupuncture [3]. In this process, a needle is electrified with microcurrent waves of bioelectricity to stimulate acupoints with different currents and frequencies generated by microcurrent waves to promote the release of endogenous substances. Due to physiological differences among animal species, animals exhibit different degrees of sensitivity to electric currents These differences in sensitivity cause some limitations in the clinical application of electroacupuncture in animals. There is great potential for electric currents to damage the body during electroacupuncture therapy in these animals [7]. How to choose the right acupoint in animals and reduce damage to the body caused by currents to improve the safety of electroacupuncture treatment is a key issue in electroacupuncture treatment
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