Development of a compact and cost-effective PET detector module for a small-animal PET system with FESA ASIC

Abstract

Due to the high cost and large channel number in positron emission tomography (PET) systems, the integration level and cost performance must be considered in the construction of commercial PET systems. In this paper, a highly integrated readout electronic system was designed and implemented based on a self-developed FESA (Front End for SiPM Arrays) readout ASIC; a compact cost-effective detector module with four lined up detector heads was built, and its performance was evaluated. Each detector head consisted of a 24× 24 LYSO crystal array (each crystal element had dimensions of 0.99 × 0.99 × 15 mm3), one end coupling to an 8 × 8 silicon photomultiplier array (SiPM array with dimensions of 3.2 × 3.2 mm2 each), and the other end covered with a 1 mm thick light guide layer. Since the front-end FESA readout chip employed a row-column summing circuit to reduce the readout channels from 64 to 16, we tried a new depth encoding method based on a single-end readout with the structure. The test results showed that the average coincidence time resolution (CTR), energy resolution, and depth of interaction (DOI) resolution of the detector are 413 ps, 15.7%, and 5.2 mm, respectively, while the crystal array in the detector head with 9-to-1 coupling can be clearly separated in the flood image. Compared with the detector head without the depth encoding ability, the clearness of the flood image was slightly decreased, but the energy resolution and time performance remained the same. We also implemented a central control board that connected all detector modules via fiber connections. The data from the detector modules could be collected over the connections, and the system central clock could be precisely distributed; therefore, the compactness of the electronics system was further enhanced.