Abstract

Starch nanoparticles (SNP) were prepared from different botanical sources (wheat, potato, mung bean, water chestnut and mango kernels) and these were further coupled with zinc oxide (ZnO) to form starch nanocomposites. The nanocomposites were characterized for their particle size, morphological properties, energy dispersive X-ray spectroscopy (EDX) and their biocompatibility was analyzed by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay, using HeLa cells. From the morphological results, it was observed that ZnO forms super molecules with SNP. Further, EDX studies also confirmed the presence of zinc in coupled molecules. The size distribution of ZnO coupled SNP from different botanical sources revealed that the average diameter of nanocomposites ranged between 506 and 1209 nm. ZnO coupled starch nanocomposites were found to be biocompatible with 77–90% cell viability up to 24 h on HeLa cells. Among all botanical sources studied, ZnO coupled mung bean starch nanocomposite showed the highest cell viability (75% up to 50 h) while ZnO coupled potato starch nanocomposite showed the lowest cell viability (65% up to 50 h).

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.