Abstract
Trimethoprim drug is an aminopyrimidine antibiotic with a methylene bridge linking the pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene functional groups.It is helpful in the treatment of UTI (Urinary Tract infection). A rapid and sensitive method was develop for the analysis of Trimethoprim in both pure and tablet dosage form. The Methanolic solution of trimethoprim pure drug at room temperature (25 ± 10C) was absorbed at a maximum of 285 nm. Under optimal and validated test conditions ,Beer's rule was obeyed in the 10 – 60 μg / ml concentration range. The experiment was conducted for linearity, accuracy, precision(Intra day & interday precision), Range, detection limits, quantification limits, robustness, and ruggedness. The trimethoprim was also analysed by preformulation parameters with respect to Melting point, solubility,determination of λmax, calibration curve .The assay of marketed formulation was also performed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
