Abstract
A simple, robust, precise, UV spectroscopic method has been developed for the simultaneous estimation of Nebivolol and Valsartan in bulk and tablet dosage forms. In this paper the estimation of those drugs was carried out by simultaneous equation method. This method is based on measurement of absorption at 281nm and 251nm i.e, λmax of Nebivolol and Valsartan respectively. The linearity observed for Nebivolol is in the range of 5-25 μg/ml and for Valsartan is in the range of 5-80 μg/ml. The accuracy of methods was assessed by recovery studies and was found to be within the range of 99.28%-99.26% for both Nebivolol and Valsartan. The developed methods were validated with respect to linearity, accuracy (recovery), and precision. The method can be employed for estimation of pharmaceutical formulations with no interference from any other excipients and diluents. The results were validated as per ICH guidelines.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
